If you are using multi-timbral plug-ins like Vienna Instruments Pro, Omnisphere, or Kontakt, you can conveniently add the available outputs of these plug-ins as dedicated input channels with the "+/–" Buttons below the volume fader of the instrument track.
In this way, you can send the audio signal back to your sequencer on a separate channel for additional mixing.

Important
Remember to assign the appropriate outputs WITHIN your multi-timbral plug-in as well.
Tip
Output routing of these additional Audio Input channels is as flexible as any other channel!